Biomedical Scientists
Job Description:
Boston Micro Fabrication Research Institute (San Diego) is looking for Biomedical Scientists.
Location: San Diego, California.
Boston Micro Fabrication is the world leader in micro-precision 3D printing industry. We are looking for highly motivated scientists with background in Cell Biology, Biomedical Engineering, Tissue Engineering, Biomaterials, Pharmaceutical sciences, or similar field. You will be part of an innovative and highly productive team committed to the convergence of cutting-edge 3D printing technology and 3D culture for drug discovery applications. We will leverage your expertise to develop in vitro 3D culture, organoids, microphysiological system, organ-on-chip platforms, and 3D culture-based assays for drug discovery, drug testing, and toxicity assessments.
Responsibilities:
- Contribute to strategic activities to develop new iPSC-based 3D culture models and applications, such as 3D microphysiological system, and organ-on-chip approaches.
- Establish in vitro 3D disease and healthy tissue models using broad cell types.
- Develop and perform quantitative validation assays with standard readout techniques in combination with bioimaging technologies to study the biological mechanisms of health and disease.
- Develop biological model-based assays for screening drug candidates.
- Effectively design and guide execution of project-specific experimental strategies, techniques, and procedure.
- Collaborate with other scientists, provide scientific leadership and mentorship to guide the research associates and technicians.
- Proactively identify issues and provide guidance to resolve project challenges while driving cross-functional collaboration to advance scientific understanding and best practice.
- Communicate and report project findings, lead the preparation of presentations and the writing of manuscripts.
- Identify and maintain collaborations regarding various technologies that can advance our product concepts.
Minimum Qualifications:
- PhD degree with a minimum of 3 years of relevant experience in Cell Biology, Biomedical Engineering, Tissue Engineering, Pharmaceutical sciences, or similar field.
- Significant hands-on experience with mammalian cell, organoid, and tissue culture.
- Extensive hands-on experience with iPSCs.
- Experience in drug discovery and related assays.
- Solid proficiency in cell-based bioanalytical assays, such as in vitro cytotoxicity assays, ELISA, gene expression analysis, PCR, immunostaining, flow cytometry, fluorescent imaging, and confocal microscopy.
- Excellent professional writing skills and the ability to maintain cooperative working relationships with a broad range of people, including staff colleagues, outside agencies and collaborators.
- Problem-solving skills sufficient to identify issues, conduct research, and develop innovative solutions.
- Experience multi-tasking in a fast-paced, highly collaborative, and diverse team environment.
Preferred Qualifications:
- Hands-on experience with primary cells and patient-derived cells.
- Demonstrated hands-on experience on advanced 3D culture, such as organoids, organ-on-chip devices, and relevant assays.
- Familiarity with handling extracellular matrix, formulating and characterizing biomaterials and biomimetic hydrogels.
- Experience with perfusion and scaffold cell culture systems.
Benefits:
Boston Micro Fabrication provides competitive compensation and benefits. Package negotiable and commensurate with qualifications, experience, and regional requirements.
Please direct resumes/applications to: Morgan Hamon, mhamon@bmf3d.com
Biomedical Research Assistant (Temporary Role)
Job Description:
Boston Micro Fabrication Research Institute (San Diego) is looking for Biomedical Research Assistant. This role is a full-time,Temporary position with potential for Permanent full-time. The initial term of the role is expected to be 12 months.
Location: San Diego, California.
Boston Micro Fabrication is the world leader in micro-precision 3D printing industry. We are looking for a Research Assistant with background in Cell Biology, Biomedical Engineering, Tissue Engineering, Pharmaceutical sciences, or similar field. You will be part of an innovative and highly productive team committed to the convergence of cutting-edge 3D printing technology and 3D culture for drug discovery applications. We will leverage your efforts to develop in vitro 3D culture, microphysiological system, organ-on-chip platforms, and 3D culture-based assays for drug discovery and toxicity assessments.
Responsibilities:
- Work under senior scientist supervision, independently, and in a team environment.
- Prepare and run experiments according to research plans.
- Perform cell culture tasks to support ongoing research projects.
- Execute assays with standard readout techniques in combination with bioimaging technologies.
- Conduct cell culture, organ-on-chip fabrication and assays; conduct other related duties and responsibilities as required.
- Analyze data, conduct troubleshooting, report research findings, prepare presentations and scientific manuscripts.
- Manage and maintain lab equipment.
- Order lab supplies and reagents.
Minimum Qualifications:
- Bachelor’s or Master’s degree with >2 years’ experience in Cell Biology, Biomedical Engineering, Tissue Engineering, Pharmaceutical sciences, or similar field.
- Excellent hands-on experience with mammalian cell culture, tissue culture, and sterile technique.
- Excellent hands-on experience in cell-based bioanalytical assays, such as in vitro cytotoxicity assays, ELISA, gene expression analysis, PCR, immunostaining, flow cytometry, and confocal microscopy.
- Experience using basic lab equipment and carrying out routine laboratory tasks.
- Knowledge of safe laboratory procedures.
- Problem-solving skills sufficient to identify issues and conduct research.
- Experience multi-tasking in a fast-paced, highly collaborative, and diverse team environment.
- Result orientated work practice with fast and high-level productivity
Preferred Qualifications:
- Hands-on experience with iPSCs, cancer cells, primary cells, and patient-derived cells.
- Hands-on experience on 3D culture, such as spheroids, organoids, organ-on-chip devices, and relevant assays.
- Familiarity with handling extracellular matrix, formulating and characterizing biomaterials.
- Drug discovery and testing knowledge and experience.
Benefits:
Boston Micro Fabrication provides competitive compensation and benefits. Package negotiable and commensurate with qualifications, experience, and regional requirements.
Please direct resumes/applications to: Sarah Vidal, svidal@bmf3d.com